Recombinant Human SMARCA4 Protein (aa 1480-1603), His-tagged

Product Details
Catalog
CPB-B005
Product Name
Recombinant Human SMARCA4 Protein (aa 1480-1603), His-tagged
Protein Name
Transcription activator BRG1
UniProt
Type
BROMODOMAINS PROTEINS
Description
High purity crystallization grade drug target recombinant proteins are ready to be shipped to customers for research purposes. The proteins have been purified to a high degree, characterized and crystallized.
Origin
Human
Source
E. coli
Gene Information
The protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein CD44. Mutations in this gene cause rhabdoid tumor predisposition syndrome type 2. Multiple transcript variants encoding different isoforms have been found for this gene.
Synonyms
BRG1, BAF190A, SNF2B, SNF2L4
Tag
His
Storage
Store at -80°C.
Applications
Research Use
Grade
Crystallography grade protein
Size
0.5mg / 1mg
* For Research Use Only.

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