Products
Inquiry

Recombinant Human SMARCA4 Protein

Product Details
Catalog
CPB-B003
Product Name
Recombinant Human SMARCA4 Protein
Protein Name
Transcription activator BRG1
UniProt
P51532
Type
BROMODOMAINS PROTEINS
Description
High purity crystallization grade drug target recombinant proteins are ready to be shipped to customers for research purposes. The proteins have been purified to a high degree, characterized and crystallized.
Origin
Human
Source
Sf9 insect cells
Gene Information
The wild type human brahma-related gene 1 (Brg1) encodes a protein of 1,647 amino acids that contains a conserved domain of the SWI2/SNF2 family necessary for normal mitotic growth and transcription regulation. BRG1 is an essential component of the SWI/SNF chromatin remodeling complexes and implicated in multiple functions through its interaction with different proteins, including the tumor suppressor protein pRb, serine-threonine kinase LKB1, and other transcription factors. Although Brg1 involves in chromatin remodeling as complexes with other SWI/SNF proteins, purified BRG1 itself is capable of remodeling mononucleosomes and nucleosomal arrays in vitro. Mutations of Brg1 have been found in multiple tumor cell lines. The wild type human BRG1 was expressed in baculovirus system and purified by an affinity column in combination with FPLC chromatography. Purified protein is greater than 95% homogeneous and contains no detectable proteases, DNase, and RNase activity.
Synonyms
BRG1, BAF190A, SNF2B, SNF2L4
Tag
N/A
Storage
Store at -80°C.
Applications
Research Use
Grade
Crystallography grade protein
Size
0.5mg / 1mg
* For Research Use Only.

Inquiry

logo

Home | About Us | Services | Applications | Resource | Contact Us | Careers
© CD ComputaBio. All rights reserved.