Antigenic determinant: It is a special chemical group with a certain composition and structure on the surface or other parts of an antigenic substance molecule that can specifically bind to its corresponding antibody or sensitized lymphocyte. The antigenic determinant whose structure has been determined is called an antigenic determinant. Here, CD ComputaBio's bioinformatician can offer you antigenic determinant prediction service to meet the specific needs of different customers.
1. Hydrophilicity: most antigenic determinants are hydrophilic;
2. On the surface of the structure: most antibodies only bind to the surface of the protein;
3. Flexible: Many known antigenic determinants are in the free movement area.
Therefore, generally speaking, the N-terminal and C-terminal of the protein are good antigenic determinant regions.
CD ComputaBio calculates the surface accessibility, hydrophilicity and flexibility of each amino acid to roughly calculate the antigenic determinant area. The antigenic determinant area should integrate the above three characteristics. The antigenic determinant prediction tool used by CD ComputaBio includes the following five algorithms:
The results of antigenic determinant prediction are shown in the form of graphs. The results of different algorithms are represented by curves in different colors, and you can select antigenic determinants by sliding the slider.
|Project name||Antigenic determinant prediction|
|Our services||CD ComputaBio offers antigenic determinant prediction service to meet the specific needs of different customers.|
|Timeline||Decide according to your needs.|
|Process||1. Submit your sequence confirmation requirements online.
2. Our technical support staff will put forward a project quotation and answer any technical questions.
3. Start production by providing a formal purchase order.
|Deliverable||We provide you with raw data and analysis service.|
CD ComputaBio' antigenic determinant prediction service can significantly reduce the cost and labor of the subsequent experiments. Antigenic determinant prediction is a personalized and customized innovative scientific research service. Each project needs to be evaluated before the corresponding analysis plan and price can be determined. If you want to know more about service prices or technical details, please feel free to contact us.