The homology modeling method is the most widely used protein prediction method. Homology modeling predicts the three-dimensional structure of target proteins based on template proteins. For proteins without experimental crystal structures, homology modeling is undoubtedly an important and effective auxiliary method. The constructed protein model can also be used for subsequent molecular mechanism exploration. Source modeling is a practical method for predicting structure from sequences. There are two prerequisites for this method: First, there are one or several distinguishable structures in the homologous protein of the target sequence. Second, the homology between the target sequence and the protein is high.
|Project name||Homology modeling services|
|Samples requirements||Our fusion protein modeling requires you to provide specific requirements.|
|Detection cycle||Decide according to your needs.|
|Service including||We provide you with raw data and modeling results.|
ComputaBio provides high-quality homology modeling services. The results can help researchers understand the structural properties of the target protein, analyze its "structure-function" relationship, and can be used for drug screening, discovery of potential therapeutic drugs for a disease, or study the interaction between the target and drug. If you need protein structure modeling service, please feel free to contact us.
Homology modeling is a general term for the conversion of primary sequences into 3D structures based on template proteins. It is currently the most effective method for protein three-dimensional structure prediction, and is widely used because of its simplicity, efficiency and high accuracy. According to the theory that the conservativeness of the three-dimensional structure of homologous proteins exceeds the protein sequence, under the premise that the identity of the protein sequence is greater than 30%, proteins with unknown structures can use one or more related structures to construct their three-dimensional structure. We provide a variety of protein structure modeling, but not limited to: