Disease Research Services

In recent years, large amounts of data from human genome sequencing, metagenome sequencing, and information about the impact of environmental and lifestyle factors on complex diseases have been produced, collected, and stored in large-scale databases. The large amount of unstudied data poses a big challenge, as well as a great opportunity, to reveal the secrets behind complex diseases using machine learning, statistics, and bioinformatics tools. Computational approaches applied to the study of various diseases are creating a new research field that takes advantage of the great progress from molecular and structural biology, immunology, bioinformatics and related areas to foster the understanding of diseases and drive innovation in treatment and diagnosis.

  • Infer complex disease-associated biomolecules including DNA, RNA, protein, methylation, and so on.
  • Study associations and interactions between complex diseases and metagenomics.
  • Identify the regulation or interactions among complex disease-associated factors at different levels.
  • Detangle the associations among multiple correlated complex diseases.
  • Re-purpose drugs for complex diseases.
  • Clinical applications of biomarkers, novel computational tools, and new drugs for complex diseases.
    • Oncology Research
      • Cervical Cancer Laryngeal Cancer Ovarian Cancer
        Chronic Lymphocytic Leukemia Liposarcoma Pancreatic Cancer
        Chronic myelogenous leukemia Lymphangioma Prostate Cancer
        Colorectal Cancer Melanoma Renal Cancer
        Endometrial Cancer Multiple Myeloma Retinopathy
        Gastrointestinal Stromal Tumor Non-hodgkin Lymphoma B cell Sarcoma
        Glioblastoma Non-Hodgkin Lymphoma T cell Small Cell Lung Cancer
        Head & Neck Cancer Non-Melanoma Skin Cancer Thyroid Cancer
        Hemangioma Non-small cell lung cancer Uterine Cancer
        Hodgkin's Lymphoma Osteosarcoma Lung Cancer
        Liver Cancer Breast Cancer Stomach Cancer
    • Metabolic Diseases Research
      • Familial Hypercholesterolemia
        Gaucher Disease
        Hunter Syndrome
        Krabbe Disease
        Maple Syrup Urine Disease
        Metachromatic Leukodystrophy
        Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS)
        Niemann-Pick
        Phenylketonuria (PKU)
        Porphyria
        Tay-Sachs Disease
        Wilson's Disease

    • Neurodegenerative Diseases Research
      • Alzheimer's Disease
        Ataxia
        Huntington's Disease
        Parkinson's Disease
        Motor Neuron Disease
        Multiple System Atrophy
        Progressive Supranuclear Palsy

    • Heart Diseases Research
      • Abnormal Heart Rhythms, or Arrhythmias
        Aorta Disease and Marfan Syndrome
        Congenital Heart Disease
        Coronary Artery Disease (narrowing of the arteries)
        Deep Vein Thrombosis and Pulmonary Embolism
        Heart Attack
        Heart Failure
        Heart Muscle Disease (cardiomyopathy)
        Heart Valve Disease
        Pericardial Disease
        Peripheral Vascular Disease
        Rheumatic Heart Disease
        Stroke
        Vascular Disease (blood vessel disease)

    • Immune Diseases Research
      • Rheumatoid Arthritis
        Systemic Lupus Erythematosus (lupus)
        Inflammatory Bowel Disease (IBD)
        Multiple Sclerosis (MS)
        Type 1 Diabetes Mellitus
        Guillain-Barre Syndrome
        Chronic Inflammatory Demyelinating Polyneuropathy
        Psoriasis

Our Services

  • Provide corresponding protein inhibitors and protein molecular docking services.
  • Optimize compounds based on the scaffolds proposed by clients.
  • Screen compounds using in silico, high-throughput, and other methods.
  • Simulate molecular dynamics between inhibitors and specific proteins encoded by the target genes.
  • Process data and analyze results using statistical techniques, such as binding affinity analysis, energy analysis and other interaction details analysis.

With combined experience in cancer drug development, CD ComputaBio's research team can perform high-quality preclinical oncology studies with industry-leading technical capabilities. Our scientists also have extensive experience in diabetes and obesity drug development. We assist researchers with experiment design, model selection, study conduct, and data analysis. Contact us for more service details.

* For Research Use Only.

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