In bioinformatics, the root-mean-square deviation (RMSD) of atomic positions is a measure of the average distance between superposed protein atoms (usually backbone atoms). The RMSD calculation can also be applied to non-protein molecules, such as small organic molecules. When studying the conformation of globular proteins, usually after the best rigid bodies are superimposed, the similarity of the three-dimensional structure is measured by the RMSD of the Cα atomic coordinates.
The root mean square fluctuation (RMSF) is used to describe the average size of the positional fluctuation of a particle group within a certain period of time. In terms of physical meaning, RMSD and RMSF both describe the deviation of the target state of the particle from the reference state. RMSD and RMSF analysis are collectively called the RMS analysis.
|Project name||RMSD, RMSF analysis service|
|Samples requirement||Please provide the original file after your calculation, if you need molecular dynamics service, you can directly provide the initial structure of PDB ID, etc.|
|Deliverables||We provide you with raw data and calculation result analysis service.|
CD ComputaBio provides corresponding RMSD, RMSF analysis services. Structure and function are the central issues of modern molecular biology. The interaction between molecules is the cornerstone of this axis problem. The interactions between molecules mainly include covalent bonds, ionic bonds, hydrogen bonds, van der Waals forces, hydrophobic interactions, etc. The CD ComputaBio team has been working in this field for more than ten years, and can provide you with accurate analysis of related forces. If you have needs in this regard, please feel free to contact us.