Reverse Virtual Screening

The reverse virtual screening method based on molecular docking has important application prospects in the field of drug target determination, new use of old drugs, and drug side effects/toxicology research. It has attracted extensive attention from researchers in the field of drug discovery. This method is the opposite of the traditional virtual screening method. For a given ligand molecule, it is necessary to select the target protein that can bind to it from the database, hence the name. The IVS method is favored by new drug developers.

Figure 1. Reverse Virtual Screening. (Zhang H.; et al.2019)

Overall solutions

Our services

CD ComputaBio can offer you but not limited to:

• Ligand-based Virtual Screening (LBVS) Service
• Structure-based Virtual Screening (SBVS) Service
• 3D-QSAR Service

CD ComputaBio' reverse virtual screening can significantly increase the hit rate of lead compounds and reduce the cost of later experimental screening. Virtual screening technology service is a personalized and customized innovative scientific research service. Each project needs to be evaluated before the corresponding analysis plan and price can be determined. If you want to know more about service prices or technical details, please feel free to contact us.

Reference:

1. Zhang H.; et al. IVS2vec: A tool of Inverse Virtual Screening based on word2vec and deep learning techniques. Methods, 2019.