Bioinformatic Analysis-Data Preprocess and Normalization Service

Our bioinformatics analysis-data preprocessing standardization services can be coupled with MS-based metabolomics. The starting point for data processing is a collection of raw data files, each file corresponding to a biological sample. The LC-MS data file is a set of sequentially recorded histograms. Each histogram represents the impact of ionized molecules on the detector in a very short time frame. The histogram consists of multiple m/z and intensity data points.

Overall solutions

The basic purpose of ComputaBio data processing is to convert raw data files into representations to help easily access the characteristics of each observed ion. These characteristics include the retention time and m/z time of the ions, and the ionic strength measurements in each raw data file. In addition to these basic features, data processing can also extract other information, such as the isotope distribution of ions.

The overall steps of data processing

Overall steps of data processing.

Because different instrument vendors use different proprietary data formats, the first step in data processing requires compatible software that can be used to analyze metabolomics data from different vendors to enable conversion of these original proprietary data. Common raw data formats include netCD and mzXML. Research groups and companies have developed converters for the latest mzXML format. A typical data processing pipeline usually goes through multiple stages, including the following step:

  • Filtering
  • Feature detection
  • Alignment
  • Normalization
  • Data analysis

Raw data are processed to remove any measurement noise or baseline. Feature detection is applied to detect representations of measured ions from the processed raw signal. Alignment methods aim to cluster measurements across separate samples and normalization removes undesired systematic variation between different samples.

Our services

Project name Bioinformatic Analysis-Data Preprocess and Normalization Service
Samples requirements Our bioinformatic analysis-data preprocess and normalization service requires you to provide specific requirements.
Detection cycle Decide according to your needs.
Service including We provide you with raw data and analysis service.
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Advantages

1. Our bioinformatics analysis-data preprocessing and standardization services save a lot of labor costs.

2. Short analysis period and fast speed.

3. The funds required are far less than biological or chemical experiments.

4. High analysis accuracy.

Bioinformatic Analysis-Data Preprocess and Normalization Service

Related services

Related Services for Bioinformatic Analysis-Data Preprocess and Normalization Service

ComputaBio provides corresponding bioinformatics analysis-data preprocessing and standardization services. Our services provides result that it is very useful for understanding the biochemical basis of physiological events. Our expert team can choose the most suitable analysis method for you, so you don't have to worry about technical issues. The ComputaBio team has been working in this field for more than ten years and has published his findings in top scientific journals.

* It should be noted that our service is only used for research, not for clinical use.

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