Post-translational modifications (PTMs) refer to the covalent modifications of polypeptides after they are synthesized, adding temporal and spatial regulation to modulate protein functions. Post-translational modifications (PTMs) are known to be essential mechanisms used by eukaryotic cells to diversify their protein functions and dynamically coordinate their signaling networks. Defects in PTMs have been linked to numerous developmental disorders and human diseases, highlighting the importance of PTMs in maintaining normal cellular states.
Figure 1. Computational modeling of post-translational modifications.
|Project name||Post-translational Modification Service|
|Our services||CD ComputaBio offers post-translational modification service to meet the specific needs of different customers.|
|Screening cycle||Decide according to your needs.|
|Deliverables||We provide you with raw data and analysis service.|
Our post-translational modification service has cooperated with many pharmaceutical companies and research institutions. Our team of experts can provide accurate modeling and analysis on the system of interest. CD ComputaBio team has been working in this field for more than ten years and has published his findings in top scientific journals. Our services may improve the understanding of the above-mentioned effects and functional results, promote the rational design of PTM regulation, and ultimately be used to guide structure-based treatments targeting modified protein systems. If you have a need for post-translational modification, please feel free to contact us.
 Wang Y C, Peterson S E, Loring J F. Protein post-translational modifications and regulation of pluripotency in human stem cells. Cell Research, 2014, 24(002):143-160.
 Fung T S, Ding X L. Post-translational modifications of coronavirus proteins: Roles and function. Future Virology, 2018, 13(2).