For decades, people have known that DNA has extremely high flexibility and polymorphism, but our understanding of its accessible conformational space is still limited. The DNA structural data, mostly from X-ray diffraction research, is sparse, and the experimental inspection of direct experiments on DNA flexibility is still subject to many restrictions. Molecular dynamics can overcome these gaps and has become a vital tool to study DNA. It provides detailed structural and dynamic insights, which illustrates its recent transition from a small number of highly specialized laboratories to various teams dealing with challenging biological problems.
Figure 1. DNA molecular dynamics simulation. (Alberto Pérez.; et al, 2012)
|Project name||DNA molecular dynamics simulation service|
|Samples requirement||The initial structure of the DNA, PDB ID, etc.|
|Timeline||Depends on the time you need to simulate.|
|Deliverables||We provide you with raw data and calculation result analysis service.|
CD ComputaBio offers a corresponding DNA molecular dynamics simulation service. Our molecular dynamics simulations provide accurate approximations of real molecular behaviors, and have proven to be very useful in understanding the biochemical basis of physiological events at different stages of drug development, even in different fields such as materials science. Our team of experts can provide up to one millisecond of simulation time for the system you choose, so you do not have to worry about technical issues. We can also analyze these results for you. The CD ComputaBio team has been working in this field for more than ten years and has published his findings in top scientific journals.