Homology Detection and Structure Comparison Service

Homology Detection and Structure Comparison Service 1

Each step of homology modeling must be checked for plausibility. Therefore, errors may be accidentally introduced and spread, so the model validation and protein evaluation is necessary. The protein model can be evaluated as a whole and in individual regions. Initially, fold of the model can be evaluated by the similarity to the template sequence, or the quality of the model can be evaluated using Ramachandran plots.

Overall solution

Homology Detection and Structure Comparison Service 2

CD ComputaBio can provide modeling service using Ramachandran plots, a visualization method used to determine whether the dihedral angles ψ and φ of amino acid residues in protein structures are within a reasonable range. It can also reflect whether the conformation of the protein is reasonable.

Homology Detection and Structure Comparison Service 3

CD ComputaBio provides Ramachandran diagram service for you. The Ramachandran diagram shows the phi and psi of all residues in the protein structure, usually glycine and original amino acids are removed and processed separately.

  • We can produce the Laplace diagram of a single amino acid or of a protein chain.
  • We can also draw the points of the disallowed area in the Laplace diagram of multiple protein chains: the disallowed area can be understood as a high-energy area, and only the energy of infinite height will cause complete disapproval.

Our services

Project name Homology detection and structure comparison service
Samples requirements Our Homology detection and structure comparison service requires you to provide specific requirements.
Detection cycle Decide according to your needs.
Service including We provide you with raw data and calculation result analysis service.
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Our advantages

  • We can provide many different modeling services, including antibody modeling and lipid modeling.
  • The calculation cycle is short and fast.
  • Compared to biological or chemical experiments, required cost for modeling is much lower.
  • The calculation accuracy is high.

Homology Detection and Structure Comparison Service 4

Our other available services:

CD ComputaBio provides corresponding homology detection and structure comparison services. Our homology detection and structure comparison services are very useful. Our team of experts can provide accurate modeling of the system you choose, so you don't have to worry about technical issues. We can also analyze these results for you. If you need homology testing and structure comparison services, please feel free to contact us.

* It should be noted that our service is only used for research, not for clinical use.

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