Pathway and Network Analysis

Demo result of pathway and network analysis.Figure 1. Demo result of pathway and network analysis.

Demo result interpretation

Figure 1 demonstrates the relationship between the significant and core pathways affacted by the experiment.

Overall solutions

  • ComputaBio will construct a signaling pathway regulatory network based on the mutual regulatory relationship between pathways in which all differential genes participate at the same time, and study the signal transduction and regulatory processes between various signaling pathways from a systematic perspective.
  • We can find the core pathway and the regulation mechanism between significant signal pathways affected by the experiment.

Summary of the Workflow

Pathway and Network Analysis 2

1. Process Data: Derive a list of differentially expressed genes from RNA sequencing data.

2. Identify Pathways: Identify enriched pathways using over-representation analysis or Gene Set Enrichment Analysis.

3. Visualize: Create an Enrichment Map displaying the landscape of pathways.

4. Build the network: Investigate and visualize functional interaction among genes in hit pathways.

5. Predict gene function: Predict the function of a gene or gene set.

6. Discover the Regulons: iRegulon - sequence based discovery of the TF, the targets and the motifs/tracks from a set of genes.

Our services

Project name Pathway and Network Analysis
Samples requirements Our network analysis services in biology require you to provide specific requirements.
Detection cycle Decide according to your needs.
Service including We provide you with raw data and modeling results.
Price Inquiry

Analysis requirements

The result of KEGG enrichment analysis or the pathway of interest in KEGG (> 10 pathways).

Pathway and Network Analysis 3

The results we provide:

  • Picture files (Network diagrams), including png, PDF formats.
  • Cytocape file: can be opened by cytoscape for detailed adjustment
  • Text file: The relationship between pathways and the indegree and outdegree corresponding to each pathway.

ComputaBio provides corresponding pathway and network analysis, which has proven to be very useful for understanding the biochemical basis of physiological events at different stages of drug development (even in different fields such as materials science). ComputaBio team has been working in this field for more than ten years and has published his findings in top scientific journals. If you have a need for network analysis services, please feel free to contact us.

We provide a variety of modeling services, but not limited to:

* It should be noted that our service is only used for research, not for clinical use.

Inquiry

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