High purity crystallization grade drug target recombinant proteins are ready to be shipped to customers for research purposes. The proteins have been purified to a high degree, characterized and crystallized.
Origin
Human
Source
E. coli
Gene Information
DYRK1A is a member of the dual-specificity tyrosine phosphorylation-regulated kinase (DYRK) family. This member contains a nuclear targeting signal sequence, a protein kinase domain, a leucine zipper motif, and a highly conservative 13-consecutive-histidin6e repeat. It catalyzes its autophosphorylation on serine/threonine and tyrosine residues. It may play a significant role in a signaling pathway regulating cell proliferation and may be involved in brain development.